I'm getting the same problem.
I've got:
Laptop running Windows 10
IE11 reinstalled
Silverlight reinstalled
Programmes run fine when I've got the reduced screen, but when I go full screen it lasts only a minute or two then tells me "Internet Explorer has stopped working - a problem caused the program to stop working correctly".
Could it have anything to do with another message I keep getting, telling me I need to update system settings? It wants me to install English language and make time format UK English - but these are already in place, and always have been.
Any help gratefully received.